Dr. Andreia Pinto and her team at the Royal Brompton Hospital have been carrying out a thorough comparison of Uranyl Acetate, UA-Zero and another UA alternative. In this published study they show the comparative performance of UA vs UA-Zero vs UAR Stain which was evaluated in a blind study by 10 electron microscopy specialists
"Anonymised images were compared by 10 electron microscopy specialists and scored based on the confidence they had in the staining. When staining sections on TEM grids, UA and UAZ gave the greater confidence in staining compared to UAR. No significant difference in confidence in staining was observed between UA and UAZ. UAZ en bloc provided staining with the highest confidence results." Read the full paper here.