London Resin's range of acrylic embedding resins are specifically formulated for the needs of the microscopist. The resins combine low viscosity, low toxicity and ease of use. Discover more about the London Resin range we manufacture here in our chemical laboratory at Agar Scientific.
LR White Resin
LR White is a hydrophilic acrylic resin of low viscosity (8 cps) available in three grades of hardness, either catalysed or uncatalysed. The resin has wide applications, being suitable for both light and electron microscopy. With appropriate fixation, the same specimen may be used for both techniques, although the soft grade is not recommended for EM use. LR White may be thermally cured or cold-cured using the accelerator. The resin has been successfully used for immunocytochemical and immunohistochemical techniques, however, it is not designed to be used at low temperatures due to the components beginning to separate out around -15°C. The low viscosity of LR White makes the resin suitable for infiltrating decalcified bone and teeth.
See below our variety of application notes for LR White resin:
- Using LR White for Electron Microscopy
- Using LR White for Hard Tissue
- Using LR White for Light Microscopy
- Using LR White for Immunohistochemistry
- Using LR White for Electron-Microscopic Immunocytochemistry
LR Gold Resin
LR Gold is designed primarily for embedding unfixed tissue at low temperatures. This process enables enzyme histochemistry and immunocytochemistry of many fixation-sensitive and temperature-labile enzymes and antigens to be carried out in 1-4µm resin sections. LR Gold is an acrylic resin with low viscosity. The resin may be cured at temperatures down to -25°C using a visible light curing source and benzil, a light-sensitive initiator. It is recommended that polyvinylpyrrolidone (PVP) is used to protect unfixed tissue from osmotic changes during processing. LR Gold has advantages over other resins for use with fixed tissue, and LR Gold can be used in the place of LR White protcols when lower temperatures are required.
Histocryl Resin Kit
Histocryl is a hydrophilic acrylic resin of low toxicity which is easy-to-use and formulated specifically for light microscopy. The resin kit permits the use of most routine staining techniques without prior removal or etching of the resin. For those laboratories using other multi-component acrylic systems, no alteration to processing schedules is necessary with Histocryl.